| ncRNA name | mmu-miR-126 |
| ncRNA Category | miRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Mus musculus |
| Tissues/Cell_line | RPE/choroids |
| Methods | transfection, qPCR, Western blot |
| Expression pattern | down-regulated |
| Functional description | miR-126 showed a significant decrease in CNV mice (p < 0.05). Both mRNA and protein levels of VEGF-A, KDR and SPRED-1 were upregulated with CNV; these changes were ameliorated by restoration of miR-126 (p < 0.05). CNV was reduced after miR-126 transfection. |
| PubMed ID | 27338342 |
| Year | 2016 |
| Title | miR-126 Regulation of Angiogenesis in Age-Related Macular Degeneration in CNV Mouse Model. |
| Drug-related ncRNA | NO |
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